Drosha regulates hMSCs cell cycle progression through a miRNA independent mechanism
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چکیده
منابع مشابه
SETD1A modulates cell cycle progression through a miRNA network that regulates p53 target genes
Expression of the p53-inducible antiproliferative gene BTG2 is suppressed in many cancers in the absence of inactivating gene mutations, suggesting alternative mechanisms of silencing. Using a shRNA screen targeting 43 histone lysine methyltransferases (KMTs), we show that SETD1A suppresses BTG2 expression through its induction of several BTG2-targeting miRNAs. This indirect but highly specific...
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ژورنال
عنوان ژورنال: The International Journal of Biochemistry & Cell Biology
سال: 2011
ISSN: 1357-2725
DOI: 10.1016/j.biocel.2011.07.005